The 7250 GC/Q-TOF - High Resolution Accurate Mass (HRAM) GCMS
The Agilent 7250 GC/Q-TOF system delivers full-spectrum, high-resolution, accurate mass data with a wide dynamic range for identifying and quantifying GC-amenable compounds. This high-resolution GC/Q-TOF enables accurate mass screening by GC/MS and enhanced compound identification through MS/MS, low-energy electron ionization, and complimentary chemical ionization techniques.
Whether it is used in complex metabolomics studies, pesticide screening in challenging matrices, or compound identification in herbal extracts, quadrupole time-of-flight GC/MS provides the ultimate in performance. Designed for real-world analysis and built for laboratory robustness, this accurate mass screening GC/MS delivers consistent confidence in results, allowing you to see the whole picture.
- GC/MS Instruments
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Product Details
Features
- Identifies compounds through high-resolution, accurate-mass data and sensitive detection
- Quantifies analytes accurately across a wide dynamic range, without compromising spectral quality
- Simplifies ambiguous data with low-energy EI for softer ionization and molecular ion enhancement (application specific)
- Supports complimentary data types with available chemical ionization for both positive and negative mode analyses
- Increases confidence in compound detection with highly efficient ionization and MassHunter SureMass algorithm for accurate and sensitive extraction of library-quality compound spectra for high match scores
- Enhances compound identification with spectral fidelity for trustworthy library matching and isotopic fidelity for generating verifiable chemical formulas
- Detects trace-level target compounds in the presence of more abundant matrix compounds with a wide in-spectrum dynamic range
- Elucidates chemical structures with MS/MS capabilities and Molecular Structure Correlator software that reveals greater detail
- Ensures excellent data quality even for narrow chromatographic peaks in high-throughput workflows with data acquisition rates of up to 50 spectra per second
- Performs screening, profiling, discovery workflows, and more, using comprehensive MassHunter software
- The built-in intelligence of the 8890 GC drives productivity with diagnostics and monitoring, and simplified access to powerful operations through the integrated touchscreen and browser interface
- Supports both flow and thermally-modulated comprehensive GCxGC for flexibility in enhanced chromatographic resolution for selective compound detection
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Technology
Gas Chromatography Mass Spectrometry (GC-MS) Information
What is GC-MS? GC/MS combines two analytical tools to identify and measure the concentration of chemicals found in foods, consumer products, pharmaceuticals, fuels, the environment, and more.
Read on to learn more about the typical components of a GC/MS instrument and its basic principle of operation.
Learn More
Applications
Literature
- Application Notes
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Introducing Semi-Automated GC/Q-TOF Screening with the AssayMAP Bravo Sample Prep Platform for Routine Antidoping Control
In this application note, the use of semi-automated GC/Q-TOF screening is described for use in routine antidoping controls, with the use of the AssayMAP Bravo for automated sample prep.
- Application Notes
- English
- 13 Sep 2023
- 2.72 MB
This work presents a novel tool to study E&L compounds with enhanced flexibility and confidence using a high-resolution accurate mass GC/Q-TOF
- Application Notes
- English
- 30 Oct 2020
- 774.28 KB
Analysis of Wastewater Effluent Samples to Identify Toxic Chemicals Using the High-Resolution Agilent 7250 GC/Q-TOF
This study utilized a workflow for broad-scope suspect screening to identify toxic chemicals in wastewater effluents.
- Application Notes
- English
- 18 Sep 2020
- 2.29 MB
Screening of Pesticides and Other Contaminants in Food Matrices Using a Novel High‑resolution GC/Q-TOF with a Low‑energy‑capable EI Source
This work describes the use of a novel high-resolution, low‑energy EI‑capable GC/Q-TOF to screen pesticides and other contaminants in food matrices.
- Application Notes
- English
- 18 Sep 2020
- 942.09 KB
Workflow for Food Classification and Authenticity using Yerba Mate and High-Resolution GC/Q-TOF
This application note provides an example of a novel food authenticity workflow that can be employed for food classification and detection of food fraud.
- Application Notes
- English
- 26 Aug 2020
- 3.08 MB
Short Chain Chlorinated Paraffins (SCCP) Analysis Using Negative Chemical Ionization (CI) and Low Energy EI by High-Resolution 7250 GC/Q-TOF
A look at the benefits of two complimentary acquisition modes of the Agilent GC/Q-TOF, negative CI and low energy EI, for SCCP analysis.
- Application Notes
- English
- 11 Oct 2019
- 1.60 MB
Contaminants Screening Using High-Resolution GC/Q-TOF and Expanded Accurate-Mass Library of Pesticides and Environmental Pollutants
Describes a workflow for strawberry extract analysis using a recently updated GC/Q-TOF accurate-mass library of pesticides and environmental contaminants.
- Application Notes
- English
- 02 Oct 2019
- 2.93 MB
Comprehensive Profiling of Environmental Contaminants in Surface Water Using High-Resolution GC/Q-TOF
A workflow using a high-resolution accurate mass GC/Q-TOF was applied to screen for environmental pollutants in water samples.A workflow using a high-resolution accurate mass GC/Q-TOF was applied to screen for environmental pollutants in water samples.
- Application Notes
- English
- 18 Sep 2019
- 5.00 MB
Combination of Chemical Ionization (CI) and Low Energy Ionization (EI) Capabilities with High-Resolution Q-TOF GC/MS
Important applications for high-resolution GC/MS systems include untargeted screening approaches as well as unknown compound identification.
- Application Notes
- English
- 24 Oct 2018
- 2.97 MB
Metabolic Changes in Lung Tissue of Tuberculosis-Infected Mice Using GC/Q-TOF with Low Energy EI
An untargeted metabolomics study was done using a novel high-resolution 7250 GC/Q-TOF to confirm the molecular ions and identify molecular formulas of unknowns.
- Application Notes
- English
- 11 Jul 2017
- 3.22 MB
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7250A Acquisition Installation Checklist
7250A Acquisition Installation Checklist
- Installation Checklists
- English
- 30 Jun 2017
- 163.01 KB
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Featured References
- Publications
- Comprehensive characterization of volatile and semi-volatile compounds in e-liquids for electronic cigarette using gas chromatography accurate mass spectrometry. M. Cobo Golpe, et al. Journal of Chromatography A 2023. Learn More
- Chemical characterization and antioxidant, anti-inflammatory, and anti-septic activities of the essential oil from the aerial parts of Atractylodes macrocephala Koidz. L. Wang, et al. Arabian Journal of Chemistry 2022. Learn More
- New analytical method for quantifying flavoring chemicals of potential respiratory health risk concerns in e-cigarette liquids. M. Page and M. Goniewicz. Frontiers in Chemistry (Lausanne, Switzerland) 2021. Learn More
- Separation and qualitative study of Ruta graveolens L. essential oil components by prep-GC, GC-QTOF-MS and NMR. Y. Li, et al. Natural Product Research 2020. Learn More
- Characterization of cabernet sauvignon wines by untargeted HS-SPME GC-QTOF-MS. A. Chavez-Marquez, et al. Molecules 2022. Learn More
- Separation and qualitative study of mentha asiatica boriss. Essential oil components by prep-GC, GC-QTOF-MS, NMR and prediction of bioactive compounds. A. Aimila, et al. Chemistry & Biodiversity 2023. Learn More
Videos
Training & Events
High Resolution GC/Q-TOF for Routine Analysis of Dioxins and Targeted and Untargeted Screening in Environmental Matrices
Gas chromatography with quadrupole time-of-flight mass spectrometry (GC/Q-TOF) is a highly versatile tool capable of doing routine chemical quantification of regulated compounds while also performing non-targeted identification of emerging pollutants in environmental samples.
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Events
News
Primer - Agilent Solutions for the Lithium-Ion Battery Industry
Unclear where to begin your lithium-ion battery testing journey? Need clarity on how to address multiple testing needs? Read Agilent's introductory guide to mineral, processing, cell component, and leak testing solutions and set your lab up for success.
- 19 Dec 2023
Agilent Announces New Revolutionary Quadrupole Mass Spectrometers at ASMS 2022
The Agilent 6475 triple quadrupole LC/MS system, 5977C GC/MSD, plus the 7000E GC/TQ and the 7010C GC/TQ represent the latest revolution in Agilent’s 50-plus year history in mass spectrometry. The new LC/TQ and GC/TQ products offer built-in instrument intelligence to simplify lab operations. The new GC/SQ and GC/TQ products with the HydroInert source help customers overcome key performance challenges with Hydrogen carrier gas.
- 06 Jun 2022
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