LC QTOF Revident quadrupole TOF innovative technology (2024)

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LC QTOF Revident quadrupole TOF innovative technology (1)

Revident LC/Q-TOF and 1290 Infinity II HPLC

The Revident LC/Q-TOF embodies the next generation of quadrupole time-of-flight instruments featuring truly innovative (electronic) instrument architecture together with instrument intelligence, a novel, ultrafast detector, and an updated, robust calibrant delivery system. Excelling in routine screening, high resolution, accurate-mass quantitation, identification of unknowns, and high-throughput testing, the Revident Q-TOF LC/MS system is ideal for small molecule applications in food safety and environmental analysis, as well as metabolomics, pharmaceutical, and forensic analyses.

Innovative technologies that will increase productivity include intelligent reflex for maximized instrument uptime, scheduled tunes and calibration for optimal performance when you need it, and new acquisition software tailored to different user roles. All new features combined result in higher throughput, which increases the bottom-line financials for your lab.

  • Quadrupole Time of Flight LC/MS

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LC QTOF Revident quadrupole TOF innovative technology (3)

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Product Details

Features

  • High resolution (Hi-Res) mass spectrometry screening can be used to increase measurement capabilities dramatically for analyses of samples with large numbers of suspects, including retrospective analysis using full mass spectra information
  • Simultaneous routine screening and quantitation using data-independent acquisition modes enable sensitive detection and identification of contaminants that maintain performance at high acquisition rates
  • Optimal instrument performance via scheduled tunes and calibration, early maintenance feedback, and instrument diagnostics increases your lab productivity
  • Intelligent reflex workflows include automatic reinjection for carryover, saturation, fast screening, suspect screening confirmation, and iterative MS/MS that allow the instrument to continuously acquire data while you focus on the results
  • New and intuitive mass spectrometry acquisition software is aligned with the LC/TQ UI, and it is simplified and tailored to different lab roles from technician to lab manager and auditor
  • Identification of unknowns is enhanced by a new software workflow for seamless batch processing and statistical analysis with subsequent identification of compounds derived from the significance analysis
  • Innovative modular design including readbacks represents highly sophisticated and complete instrument diagnostics, with all relevant information constantly monitored, allowing for fast and reliable detection of the individual component’s status
  • A completely new detector based on analog-to-digital conversion (ADC) generates mass peaks with high resolution and isotope fidelity, with the obtained peak symmetry maintaining high mass accuracy through different abundance levels
  • New delivery system for calibrant and reference masses is pump-based and flow-controlled, permitting constant and reliable flow rates

Specifications

IDL Sensitivity (negative)
  • <45fg chloramphenicol on column, <45 ppt
  • IDL spec only for new LC/MS systems using Agilent Jet Stream + checkout column + 1290 Infinity II LC
IDL Sensitivity (positive)
  • <40fg reserpine on column, <40 ppt
  • IDL spec only for new LC/MS systems using Agilent Jet Stream + checkout column + 1290 Infinity II LC
In-spectra Dynamic Range
  • 5 Orders
Ion Source
  • Dual-AJS
  • Dual-ESI
  • APCI
Isotope Fidelity
  • <5 %
MS Acquisition Rate
  • 50 spectra/second
MS Mass Accuracy (negative)
  • <0.6 ppm RMS
MS Mass Accuracy (positive)
  • <0.5 ppm RMS
MS Sensitivity (negative)
  • S/N (RMS) > 750:1. Measured with 1pg chloramphenicol on column
MS Sensitivity (positive)
  • S/N (RMS) > 1000:1. Measured with 1pg reserpine on column
MS/MS Acquisition Rate
  • 50 spectra/second
MS/MS Mass Accuracy (negative)
  • <2 ppm RMS
MS/MS Mass Accuracy (positive)
  • <2 ppm RMS
MS/MS Sensitivity (negative)
  • S/N (RMS) > 3000:1. Measured with 1pg chloramphenicol on column
MS/MS Sensitivity (positive)
  • S/N (RMS) > 3000:1. Measured with 1pg reserpine on column
Polarity Switching Duty Cycle
  • 1.0 s
Quad Resolution (FWHM)
  • 1.3 Da (autotune)
Quadrupole Isolation Mass Range
  • m/z 20-4000
Software Platform
  • MassHunter
Supported Software Add-Ons
  • MassHunter BioConfirm
  • MassHunter VistaFlux
  • Mass Profiler Professional
  • Classifier
  • Lipid Annotator
  • MassHunter Explorer
TOF Mass Range
  • m/z 20-10,000
TOF Mass Resolution (FWHM)
  • > 35,000 at m/z 118 independent of acquisition rate
  • > 60,000 at m/z 2,722 independent of acquisition rate
Temperature Mass Stability
  • <1 ppm / 3 °C
Ventless Maintenance
  • VacShield Technology

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How It Works

Applications

Literature

Brochures

Intelligence That Inspires Insight - Agilent Revident LC/Q-TOF System

Enhanced with multiple workflow capabilities, the Revident LC/Q-TOF lets you identify—and quickly assess—compounds in question.

  • Brochures
  • English
  • 14 Dec 2023
  • 10.60 MB
  • PDF
Posters

Videos

Technology

Additional Technology and Software Capabilities for LC/Q-TOF

Agilent partners with selected companies who provide technologies and software that expand the core capabilities of the LC/Q-TOF portfolio. Learn more about additional capabilities and visit the compatibility matrix to see which ones are offered for your LC/Q-TOF!

Learn More

Support

Site Preparation Checklists

Revident LC/QTOF Site Preparation Checklist

Site preparation information for the Revident LC/QTOF system

  • Site Preparation Checklists
  • English
  • 06 Nov 2023
  • 238.63 KB
  • PDF

MassHunter Workstation and Networked Workstation for LC/TOF and LC/QTOF Systems Software Site Preparation Checklist

This site preparation checklist applies to MassHunter Acquisition for TOF/QTOF 11.0 and higher, MassHunter Quantitative analysis 11.0 and higher, MassHunter BioConfirm 11.0 and higher, and MassHunter Qualitative Analysis 10.0 and higher running in Workstation and Networked Workstation configurations.

  • Site Preparation Checklists
  • English
  • 28 Nov 2023
  • 580.22 KB
  • PDF
User Manuals

Training & Events

The PFAS legacy in our urban environment

Per- and polyfluoroalkyl substances (PFAS) are emerging contaminants attracting global scientific and regulatory attention due to their environmental persistence and bioaccumulative properties.

Webinar/Training

News

Agilent Announces Inspirational LC/TQ and LC/Q-TOF Mass Spectrometry Solutions at ASMS 2023

Agilent Technologies announced two new liquid chromatography mass spectrometry systems (LCMS), the Agilent 6495D LC/TQ and the Agilent Revident LC/Q-TOF. Facilitating the high-end performance of the Revident LC/Q-TOF, Agilent is also announcing the new Agilent MassHunter Explorer Profiling software and the new Agilent ChemVista library manager software.

  • 05 Jun 2023

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LC QTOF Revident quadrupole TOF innovative technology (2024)
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